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| thromboangiitis obliterans ： ウィキペディア英語版 |
thromboangiitis obliterans
:''Not to be confused with Berger's disease (IgA nephropathy)''
Thromboangiitis obliterans (also known as Buerger's disease, Buerger disease (; German ), or presenile gangrene ) is a recurring progressive inflammation and thrombosis (clotting) of small and medium arteries and veins of the hands and feet. It is strongly associated with use of tobacco products, primarily from smoking, but also from smokeless tobacco.
==Signs and symptoms==
There is a recurrent acute and chronic inflammation and thrombosis of arteries and veins of the hands and feet. The main symptom is pain in the affected areas, at rest and while walking (claudication).〔 The impaired circulation increases sensitivity to cold. Peripheral pulses are diminished or absent. There are color changes in extremity. The colour may range from cyanotic blue to reddish blue. Skin becomes thin and shiny. Hair growth is reduced. Ulcerations and gangrene in the extremities are common complications, often resulting in the need for amputation of the involved extremity.
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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